SEMAX (10MG)

What is SEMAX (10MG)?

Semax is a synthetic heptapeptide analogue derived from the fragment of Adrenocorticotropic Hormone (ACTH) (4-10). Its amino acid sequence is Met–Glu–His–Phe–Pro–Gly–Pro (MEHFPGP) or close variants thereof. It was developed in Russia in the 1980s for neuroprotective and cognitive research applications. Semax is notable in that it retains neurotropic and nootropic properties of ACTH fragments while largely lacking classical hormonal effects of full-length ACTH.

Chemical Structure of SEMAX (10MG)

• Sequence: Met–Glu–His–Phe–Pro–Gly–Pro (often abbreviated MEHFPGP)

• Molecular formula: C₃₇H₅₁N₉O₁₀S

• Approximate molecular weight: ~813.9 g/mol

• CAS Number: 80714-61-0

• Appearance & form: White to off-white lyophilized powder (≥95% HPLC purity for research compounds)

What Are the Effects of SEMAX (10MG)?

Neuroprotection & Gene Expression Modulation — Semax has been shown in rodent models of cerebral ischemia (stroke) to modulate gene expression of neurotrophic factors (such as BDNF) and their receptors, reduce markers of immune/inflammatory stress and support neural tissue survival.
Cognitive Enhancement & Neurotransmitter Support — Studies indicate Semax increases BDNF/TrkB expression in the hippocampus and elevates neurotransmitter levels (dopamine, serotonin) in brain regions tied to cognition and mood. 
Immunomodulation & Stress Resilience — Semax affects stress-induced behavioral models in animals, reducing anhedonia and adrenal hypertrophy in chronic stress paradigms; it may also interact with metal-ion binding and oxidative stress pathways. 
Research Use Only — While used clinically in Russia for certain neurological conditions, in many jurisdictions Semax remains a research compound and its full safety/efficacy profile in humans is not established by large-scale trials.

Legal & Safety Disclaimer

This product is for research use only. It is not approved for human or veterinary consumption, medical treatment, or as a dietary supplement. Use only in controlled laboratory settings by qualified personnel. Keep out of reach of children. The supplier verifies only the purity and identity of the material and does not claim any therapeutic benefit.